XBridge BEH Phenyl 色谱柱
• 高化学稳定的Ⅱ 型苯基柱
• 对芳香化合物有独特的选择性
• 三键键合方式，有效提高苯基抗流失性，避免苯基流失本底峰（UV），兼容LC/MS
• 温度上限：低pH时80℃，高pH时60℃
BEH颗粒能够显著改善色谱峰形的关键因素是其在合成工艺中 采用了亚乙基桥结构。亚乙基桥连接相邻的两个硅醇基，这 不仅增加了颗粒强度，同时也减少了游离的硅醇基位点，从 而减少硅醇基与样品间不利的相互作用力。传统的方法(例如 大量的封端(excessive end capping))仅限于封端试剂的空间位阻 效应及在活性位点上连接配体。这样，残余的游离硅醇基暴 露后就会导致峰展宽和峰拖尾。亚乙基桥可减少游离的硅醇 基数量，使分子空间排布最适于配体键合及封端。控制这一 过程可有助于XBridge色谱柱得到卓越的峰形。
色谱柱在低pH流动相中柱寿命差的主要原因是键合相在酸性条件下发生水解。XBridge填料采用沃特世先进的键合技术与封端技术，可以在低pH条件下表现出良好的配体稳定性与色谱重现性。
Advantages of CORTECS C18 2.7 μm and XBridge BEH Phenyl X P 2.5 μm Columns for the Analysis of a Comprehensive Panel of Pain Management Drugs for Forensic Toxicology
In forensic toxicology, drug screening panels often include such commonly used substances such as opiates, benzodiazepines and stimulants. These panels are often analyzed by LC-MS using traditional C18 column technologies. Key considerations include the ability to chromatographically resolve the various pairs of isobaric compounds included in these panels, while maintaining good peak shape for a variety of compounds. In addition, when using traditional HPLC systems, the ability to analyze samples as rapidly as possible without exceeding the pressure limitations of the system is very important. This application note highlights the capabilities of Waters’ new CORTECS C18 2.7 μm Columns and XBridge BEH Phenyl XP 2.5 μm Columns for this type of application. In the case of the CORTECS C18 Column, the high efficiency packing of solid core 2.7 μm particles yields excellent performance that equals or exceeds competitive columns at lower operating backpressures. If alternative selectivity is desired, the phenyl functionality of the BEH phenyl column enhances the retention of opiate compounds. This enhanced retention can potentially result in reducing ion suppression from urinary matrix components. Both columns achieve excellent baseline separation between isomers, and the entire panel of 35 compounds, including opioids, benzodiazepines, stimulants, and other drugs of abuse can be analyzed in under 4 minutes at backpressures compatible with any HPLC system
品名 | 编号 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 4.6 mm X 100 mm, 1/pkg | 186003351 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 4.6 mm X 30 mm, 1/pkg | 186003331 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 4.6 mm X 50 mm, 1/pkg | 186003332 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 4.6 mm X 75 mm, 1/pkg | 186003333 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 2.1 mm X 100 mm, 1/pkg | 186003339 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 2.1 mm X 50 mm, 1/pkg | 186003338 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 1 mm X 50 mm, 1/pkg | 186003317 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 4.6 mm X 150 mm, 1/pkg | 186003335 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 4.6 mm X 100 mm, 1/pkg | 186003334 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 2.1 mm X 30 mm, 1/pkg | 186003337 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 4.6 mm X 250 mm, 1/pkg | 186003965 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 2.1 mm X 150 mm, 1/pkg | 186003340 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 3 mm X 100 mm, 1/pkg | 186003344 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 3 mm X 50 mm, 1/pkg | 186003343 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 3 mm X 30 mm, 1/pkg | 186003342 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 2.1 mm X 30 mm, 1/pkg | 186003321 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 2.1 mm X 50 mm, 1/pkg | 186003322 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 3 mm X 150 mm, 1/pkg | 186003329 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 3 mm X 100 mm, 1/pkg | 186003328 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 3 mm X 50 mm, 1/pkg | 186003327 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 3 mm X 30 mm, 1/pkg | 186003326 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 2.1 mm X 150 mm, 1/pkg | 186003324 |
XBridge BEH Phenyl Column, 130Å, 3.5 µm, 2.1 mm X 100 mm, 1/pkg | 186003323 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 3 mm X 150 mm, 1/pkg | 186003345 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 3 mm X 250 mm, 1/pkg | 186003346 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 4.6 mm X 75 mm, 1/pkg | 186003350 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 4.6 mm X 250 mm, 1/pkg | 186003353 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 4.6 mm X 150 mm, 1/pkg | 186003352 |
XBridge BEH Phenyl Intelligent Speed (IS) Column, 130Å, 3.5 µm, 4.6 mm X 20 mm, 1/pkg | 186003330 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 2.5 µm, 4.6 mm X 150 mm, 3/pkg | 186006778 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 2.5 µm, 3 mm X 150 mm, 3/pkg | 186006777 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 2.5 µm, 2.1 mm X 150 mm, 3/pkg | 186006776 |
XBridge BEH Phenyl Intelligent Speed (IS) Column, 130Å, 5 µm, 2.1 mm X 20 mm, 1/pkg | 186003336 |
XBridge BEH Phenyl Intelligent Speed (IS) Column, 130Å, 3.5 µm, 2.1 mm X 20 mm, 1/pkg | 186003320 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 2.5 µm, 4.6 mm X 50 mm, 3/pkg | 186006219 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 2.5 µm, 3 mm X 100 mm, 3/pkg | 186006218 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 2.5 µm, 2.1 mm X 100 mm, 3/pkg | 186006216 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 2.5 µm, 2.1 mm X 50 mm, 3/pkg | 186006215 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 3.5 µm, 2.1 mm X 100 mm, 3/pkg | 186003799 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 3.5 µm, 4.6 mm X 150 mm, 3/pkg | 186003803 |
XBridge BEH Phenyl Intelligent Speed (IS) Column, 130Å, 3.5 µm, 3 mm X 20 mm, 1/pkg | 186003325 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 3.5 µm, 4.6 mm X 100 mm, 3/pkg | 186003802 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 3.5 µm, 3 mm X 150 mm, 3/pkg | 186003801 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 3.5 µm, 3 mm X 100 mm, 3/pkg | 186003800 |
XBridge BEH Phenyl Intelligent Speed (IS) Column, 130Å, 5 µm, 4.6 mm X 20 mm, 1/pkg | 186003347 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 5 µm, 4.6 mm X 100 mm, 3/pkg | 186003807 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 4.6 mm X 30 mm, 1/pkg | 186003348 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 5 µm, 3 mm X 100 mm, 3/pkg | 186003805 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 5 µm, 2.1 mm X 150 mm, 3/pkg | 186003804 |
XBridge BEH Phenyl Column, 130Å, 5 µm, 4.6 mm X 50 mm, 1/pkg | 186003349 |
XBridge BEH Phenyl OBD Prep Column, 130Å, 5 µm, 30 mm X 50 mm, 1/pkg | 186003277 |
XBridge BEH Phenyl OBD Prep Column, 130Å, 5 µm, 30 mm X 75 mm, 1/pkg | 186003278 |
XBridge BEH Phenyl Prep Guard Cartridge, 130Å, 5 µm, 19 mm X 10 mm, 1/pkg | 186003355 |
XBridge BEH Phenyl OBD Prep Column, 130Å, 5 µm, 30 mm X 150 mm, 1/pkg | 186003276 |
XBridge BEH Phenyl Prep Guard Cartridge, 130Å, 5 µm, 10 mm X 10 mm, 1/pkg | 186003354 |
XBridge BEH Phenyl XP Column, 130Å, 2.5 µm, 2.1 mm X 150 mm, 3/pkg | 176002885 |
XBridge BEH Phenyl Prep Guard Cartridge, 130Å, 5 µm, 30 mm X 10 mm, 1/pkg | 186006891 |
XBridge BEH Phenyl OBD Prep Column, 130Å, 5 µm, 50 mm X 100 mm, 1/pkg | 186003940 |
XBridge BEH Phenyl XP Column, 130Å, 2.5 µm, 2.1 mm X 30 mm, 1/pkg | 186006064 |
XBridge BEH Phenyl OBD Prep Column, 130Å, 5 µm, 19 mm X 50 mm, 1/pkg | 186003356 |
XBridge BEH Phenyl OBD Prep Column, 130Å, 5 µm, 19 mm X 100 mm, 1/pkg | 186003357 |
XBridge BEH Phenyl OBD Prep Column, 130Å, 5 µm, 19 mm X 150 mm, 1/pkg | 186003358 |
XBridge BEH Phenyl OBD Prep Column, 130Å, 5 µm, 30 mm X 100 mm, 1/pkg | 186003279 |
XBridge BEH Phenyl XP Column, 130Å, 2.5 µm, 2.1 mm X 100 mm, 1/pkg | 186006067 |
XBridge BEH Phenyl XP Column, 130Å, 2.5 µm, 2.1 mm X 150 mm, 1/pkg | 186006718 |
XBridge BEH Phenyl OBD Prep Column, 130Å, 5 µm, 50 mm X 50 mm, 1/pkg | 186003936 |
XBridge BEH Phenyl OBD Prep Column, 130Å, 5 µm, 19 mm X 250 mm, 1/pkg | 186004024 |
XBridge BEH Phenyl Method Validation Kit, XP Column, 130Å, 2.5 µm, 3 mm X 50 mm, 3/pkg | 186006217 |
XBridge BEH Phenyl VanGuard Cartridge, 130Å, 5 µm, 3.9 mm X 5 mm, 3/pkg | 186007798 |
XBridge BEH Phenyl XP Column, 130Å, 2.5 µm, 2.1 mm X 100 mm, 3/pkg | 176002573 |
XBridge BEH Phenyl VanGuard Cartridge, 130Å, 5 µm, 2.1 mm X 5 mm, 3/pkg | 186007796 |
XBridge BEH Phenyl VanGuard Cartridge, 130Å, 3.5 µm, 3.9 mm X 5 mm, 3/pkg | 186007795 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 5 µm, 4.6 mm X 250 mm, 3/pkg | 186003809 |
XBridge BEH Phenyl VanGuard Cartridge, 130Å, 3.5 µm, 2.1 mm X 5 mm, 3/pkg | 186007793 |
XBridge BEH Phenyl Method Validation Kit, 130Å, 5 µm, 4.6 mm X 150 mm, 3/pkg | 186003808 |
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