CORTECS UPLC 1.6 µm实心核颗粒色谱柱。当与低扩散体积的UPLC系统使用时，它能够提供最高级别的柱效。与粒径相当的全多孔填料相比，CORTECS UPLC 1.6 µm实心核颗粒柱可以给出更尖锐、更窄的色谱峰。到现在我们已经发展出7种独特的CORTECS色谱柱键合相，包括从反相到HILIC柱，以便分离性质不同的各种分析物。
与相似粒径的全多孔颗粒相比，实心核颗粒因其形态特征的特殊性而更有可能获得更高柱效。要实现这个理论柱效，还需要配合正确的色谱柱硬件和最佳的柱装填技术。沃特世凭借UPLC柱生产经验，采用超低扩散的色谱柱硬件与独家柱装填技术，配合全新CORTECS颗粒，树立了UPLC色谱柱柱效新标准。
基于2010年沃特世成功推出的表面带电杂化颗粒技术(CSH™)，为颗粒表面赋予少量正电荷，可以使用低离子强度的流动相(如甲酸)，对碱性化合物以及肽仍能获得卓越的峰形与载量。
采用CORTECS HILIC色谱柱改善极性分析物的保留性能，亲水作用色谱(HILIC)是一种对在反相色谱中保留性能较差的强极性分析物进行有效保留的模式。CORTECS HILIC色谱柱所含的未键合实心颗粒可以保留极性化合物。在反相色谱中，通常采用高比例水相流动相来保留极性分析物，HILIC则是使用含有高比例有机溶剂的流动相实现对极性分析物的保留。
背景：在液相色谱分析中，如果样品运行过程 十分耗时，那么会由于对宝贵仪器的长 时间占用和处理样品数目的限制，导致 实验室整体工作效率降低。通过缩短样 品分析时间来提高样品通量是很困难的， 因为常常需要牺牲分离度或灵敏度等重 要色谱属性。然而，采用CORTECS UPLC色谱柱就可以在保持峰容量的同时提高样品通量。
解决方案：高效的CORTECS UPLC色谱柱采用了先进的 实心核颗粒和填充技术，能够在高流速 下保持良好的分离性能。这让色谱工作 者可以根据需要提高方法的流速，进而缩短运行时间并提高通量，而且无需牺 牲分离质量。图1所示为使用 CORTECS UPLC C18 +色谱柱分析磺胺类药物，并使用 全多孔C18色谱柱进行初始分离的结果比 较。CORTECS UPLC C18+色谱柱流速为初始 分离的两倍，并按照流速变化对梯度作 出相应调整。
品名 | 编号 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 2.1 mm X 150 mm, 3/pkg | 176003931 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 100 mm, 3/pkg | 186008699 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 3 mm X 30 mm, 3/pkg | 176003932 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 75 mm, 3/pkg | 186008698 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 3 mm X 50 mm, 3/pkg | 176003933 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 3 mm X 75 mm, 3/pkg | 176003934 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 2.1 mm X 150 mm, 1/pkg | 186008695 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 2.1 mm X 100 mm, 1/pkg | 186008694 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 50 mm, 3/pkg | 186008697 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 30 mm, 3/pkg | 186008696 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 2.1 mm X 100 mm, 3/pkg | 176003930 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 2.1 mm X 30 mm, 1/pkg | 186008691 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 2.1 mm X 75 mm, 1/pkg | 186008693 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 1/pkg | 186008692 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 150 mm, 3/pkg | 186008700 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 3 mm X 30 mm, 1/pkg | 186008701 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 3 mm X 150 mm, 1/pkg | 186008705 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 3 mm X 100 mm, 1/pkg | 186008704 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 3 mm X 75 mm, 1/pkg | 186008703 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 3 mm X 50 mm, 1/pkg | 186008702 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 2.1 mm X 75 mm, 3/pkg | 176003929 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 3/pkg | 176003928 |
CORTECS T3 VanGuard Cartridge, 120Å, 2.7 µm, 3.9 mm X 5 mm, 3/pkg | 186008507 |
CORTECS T3 VanGuard Pre-column, 120Å, 1.6 µm, 2.1 mm X 5 mm, 3/pkg | 186008508 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 2.1 mm X 30 mm, 3/pkg | 176003927 |
CORTECS UPLC T3 Column, 120Å, 1.6 µm, 2.1 mm X 150 mm, 1/pkg | 186008500 |
CORTECS UPLC T3 Method Validation Kit, 120Å, 1.6 µm, 2.1 mm X 100 mm, 3/pkg | 186008536 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 3 mm X 150 mm, 3/pkg | 186008710 |
CORTECS UPLC T3 Method Validation Kit, 120Å, 1.6 µm, 2.1 mm X 150 mm, 3/pkg | 186008537 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 3 mm X 100 mm, 3/pkg | 186008709 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 3 mm X 75 mm, 3/pkg | 186008708 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 3 mm X 50 mm, 3/pkg | 186008707 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 3 mm X 30 mm, 3/pkg | 186008706 |
CORTECS UPLC T3 Column, 120Å, 1.6 µm, 3 mm X 100 mm, 1/pkg | 186008504 |
CORTECS UPLC T3 Column, 120Å, 1.6 µm, 3 mm X 150 mm, 1/pkg | 186008505 |
CORTECS UPLC T3 Column, 120Å, 1.6 µm, 2.1 mm X 30 mm, 1/pkg | 186008496 |
CORTECS UPLC T3 Column, 120Å, 1.6 µm, 2.1 mm X 50 mm, 1/pkg | 186008497 |
CORTECS UPLC T3 Column, 120Å, 1.6 µm, 2.1 mm X 100 mm, 3/pkg | 176003894 |
CORTECS UPLC T3 Column, 120Å, 1.6 µm, 2.1 mm X 75 mm, 1/pkg | 186008498 |
CORTECS UPLC T3 Column, 120Å, 1.6 µm, 2.1 mm X 150 mm, 3/pkg | 176003895 |
CORTECS UPLC T3 Column, 120Å, 1.6 µm, 2.1 mm X 100 mm, 1/pkg | 186008499 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 3/pkg | 176003147 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 2.1 mm X 75 mm, 3/pkg | 176003148 |
CORTECS UPLC C18 Method Validation Kit, 90Å, 1.6 µm, 3 mm X 150 mm, 3/pkg | 186007165 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 3 mm X 100 mm, 1/pkg | 186007100 |
CORTECS UPLC C18 Method Validation Kit, 90Å, 1.6 µm, 3 mm X 30 mm, 3/pkg | 186007161 |
CORTECS UPLC C18 Method Validation Kit, 90Å, 1.6 µm, 3 mm X 50 mm, 3/pkg | 186007162 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 3 mm X 150 mm, 1/pkg | 186007102 |
CORTECS UPLC C18 Method Validation Kit, 90Å, 1.6 µm, 3 mm X 75 mm, 3/pkg | 186007163 |
CORTECS UPLC C18 Method Validation Kit, 90Å, 1.6 µm, 3 mm X 100 mm, 3/pkg | 186007164 |
CORTECS UPLC C18 VanGuard Pre-column, 90Å, 1.6 µm, 2.1 mm X 5 mm, 3/pkg | 186007123 |
CORTECS UPLC C18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 150 mm, 3/pkg | 186007160 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 3 mm X 75 mm, 1/pkg | 186007099 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 3 mm X 50 mm, 1/pkg | 186007098 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 3 mm X 30 mm, 1/pkg | 186007097 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 2.1 mm X 75 mm, 1/pkg | 186007094 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 1/pkg | 186007093 |
CORTECS UPLC C18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 30 mm, 3/pkg | 186007156 |
CORTECS UPLC C18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 50 mm, 3/pkg | 186007157 |
CORTECS UPLC C18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 75 mm, 3/pkg | 186007158 |
CORTECS UPLC C18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 100 mm, 3/pkg | 186007159 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 3 mm X 150 mm, 3/pkg | 176003155 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 3 mm X 100 mm, 3/pkg | 176003154 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 3 mm X 75 mm, 3/pkg | 176003153 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 3 mm X 50 mm, 3/pkg | 176003152 |
CORTECS UPLC C18 Column, 90Å, 1.6 µm, 3 mm X 30 mm, 3/pkg | 176003151 |
CORTECS UPLC C18+ Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 150 mm, 3/pkg | 186007180 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 2.1 mm X 75 mm, 3/pkg | 176003168 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 2.1 mm X 100 mm, 3/pkg | 176003169 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 3 mm X 75 mm, 1/pkg | 186007120 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 3/pkg | 176003167 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 2.1 mm X 30 mm, 3/pkg | 176003166 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 3 mm X 150 mm, 1/pkg | 186007122 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 3 mm X 100 mm, 1/pkg | 186007121 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 3 mm X 30 mm, 1/pkg | 186007118 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 3 mm X 50 mm, 1/pkg | 186007119 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 3 mm X 75 mm, 3/pkg | 176003173 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 3 mm X 100 mm, 3/pkg | 176003174 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 3 mm X 30 mm, 3/pkg | 176003171 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 3 mm X 50 mm, 3/pkg | 176003172 |
CORTECS UPLC C18+ Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 75 mm, 3/pkg | 186007178 |
CORTECS UPLC C18+ Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 100 mm, 3/pkg | 186007179 |
CORTECS UPLC C18+ Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 30 mm, 3/pkg | 186007176 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 3 mm X 150 mm, 3/pkg | 176003175 |
CORTECS UPLC C18+ Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 50 mm, 3/pkg | 186007177 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 2.1 mm X 30 mm, 1/pkg | 186007113 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 2.1 mm X 150 mm, 1/pkg | 186007117 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 2.1 mm X 150 mm, 3/pkg | 176003170 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 2.1 mm X 100 mm, 1/pkg | 186007116 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 2.1 mm X 75 mm, 1/pkg | 186007115 |
CORTECS UPLC C18+ Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 1/pkg | 186007114 |
CORTECS UPLC C18+ Method Validation Kit, 90Å, 1.6 µm, 3 mm X 50 mm, 3/pkg | 186007182 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 2.1 mm X 150 mm, 1/pkg | 186007107 |
CORTECS UPLC C18+ Method Validation Kit, 90Å, 1.6 µm, 3 mm X 30 mm, 3/pkg | 186007181 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 3 mm X 30 mm, 1/pkg | 186007108 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 3 mm X 50 mm, 1/pkg | 186007109 |
CORTECS UPLC C18+ Method Validation Kit, 90Å, 1.6 µm, 3 mm X 150 mm, 3/pkg | 186007185 |
CORTECS UPLC C18+ Method Validation Kit, 90Å, 1.6 µm, 3 mm X 100 mm, 3/pkg | 186007184 |
CORTECS UPLC C18+ Method Validation Kit, 90Å, 1.6 µm, 3 mm X 75 mm, 3/pkg | 186007183 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 3 mm X 150 mm, 3/pkg | 176003165 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 3 mm X 100 mm, 3/pkg | 176003164 |
CORTECS UPLC C18+ VanGuard Pre-column, 90Å, 1.6 µm, 2.1 mm X 5 mm, 3/pkg | 186007125 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 3 mm X 30 mm, 3/pkg | 176003161 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 1/pkg | 186007104 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 2.1 mm X 150 mm, 3/pkg | 176003160 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 2.1 mm X 30 mm, 1/pkg | 186007103 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 2.1 mm X 100 mm, 1/pkg | 186007106 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 3 mm X 50 mm, 3/pkg | 176003162 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 2.1 mm X 75 mm, 1/pkg | 186007105 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 2.1 mm X 100 mm, 3/pkg | 176003159 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 3/pkg | 176003157 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 2.1 mm X 75 mm, 3/pkg | 176003158 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 2.1 mm X 30 mm, 3/pkg | 176003156 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 3 mm X 150 mm, 1/pkg | 186007112 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 3 mm X 100 mm, 1/pkg | 186007111 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 3 mm X 75 mm, 1/pkg | 186007110 |
CORTECS C8 Column, 90Å, 1.6 µm, 2.1 mm X 100 mm, 1/pkg | 186008401 |
CORTECS C8 Column, 90Å, 1.6 µm, 2.1 mm X 150 mm, 1/pkg | 186008402 |
CORTECS C8 Column, 90Å, 1.6 µm, 3 mm X 100 mm, 3/pkg | 176003837 |
CORTECS C8 Column, 90Å, 1.6 µm, 2.1 mm X 75 mm, 1/pkg | 186008400 |
CORTECS C8 Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 1/pkg | 186008399 |
CORTECS C8 Column, 90Å, 1.6 µm, 2.1 mm X 30 mm, 1/pkg | 186008398 |
CORTECS C8 Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 3/pkg | 176003830 |
CORTECS C8 Column, 90Å, 1.6 µm, 2.1 mm X 75 mm, 3/pkg | 176003831 |
CORTECS C8 Column, 90Å, 1.6 µm, 2.1 mm X 100 mm, 3/pkg | 176003832 |
CORTECS C8 Column, 90Å, 1.6 µm, 2.1 mm X 150 mm, 3/pkg | 176003833 |
CORTECS UPLC HILIC Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 100 mm, 3/pkg | 186007169 |
CORTECS UPLC HILIC Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 30 mm, 3/pkg | 186007166 |
CORTECS UPLC HILIC Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 50 mm, 3/pkg | 186007167 |
CORTECS UPLC HILIC Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 75 mm, 3/pkg | 186007168 |
CORTECS UPLC HILIC Column, 90Å, 1.6 µm, 3 mm X 75 mm, 3/pkg | 176003163 |
CORTECS UPLC HILIC VanGuard Pre-column, 90Å, 1.6 µm, 2.1 mm X 5 mm, 3/pkg | 186007124 |
CORTECS C8 Column, 90Å, 1.6 µm, 3 mm X 100 mm, 1/pkg | 186008411 |
CORTECS C8 Column, 90Å, 1.6 µm, 2.1 mm X 30 mm, 3/pkg | 176003829 |
CORTECS C8 Column, 90Å, 1.6 µm, 3 mm X 150 mm, 1/pkg | 186008412 |
CORTECS UPLC HILIC Method Validation Kit, 90Å, 1.6 µm, 3 mm X 100 mm, 3/pkg | 186007174 |
CORTECS UPLC HILIC Method Validation Kit, 90Å, 1.6 µm, 3 mm X 150 mm, 3/pkg | 186007175 |
CORTECS UPLC HILIC Method Validation Kit, 90Å, 1.6 µm, 3 mm X 50 mm, 3/pkg | 186007172 |
CORTECS UPLC HILIC Method Validation Kit, 90Å, 1.6 µm, 3 mm X 75 mm, 3/pkg | 186007173 |
CORTECS UPLC HILIC Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 150 mm, 3/pkg | 186007170 |
CORTECS UPLC HILIC Method Validation Kit, 90Å, 1.6 µm, 3 mm X 30 mm, 3/pkg | 186007171 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 2.1 mm X 150 mm, 3/pkg | 176003931 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 100 mm, 3/pkg | 186008699 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 3 mm X 30 mm, 3/pkg | 176003932 |
CORTECS UPLC Shield RP18 Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 75 mm, 3/pkg | 186008698 |
CORTECS UPLC Shield RP18 Column, 90Å, 1.6 µm, 3 mm X 50 mm, 3/pkg | 176003933 |
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